Circulating extracellular vesicles from patients with valvular heart disease induce neutrophil chemotaxis via FOXO3a and the inhibiting role of dexmedetomidine

We previously demonstrated that circulating extracellular vesicles (EVs) from patients with valvular heart disease (VHD; vEVs) contain inflammatory components and inhibit endothelium-dependent vasodilation. Neutrophil chemotaxis plays a key role in renal dysfunction, and dexmedetomidine (DEX) can re...

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Veröffentlicht in:	American journal of physiology: endocrinology and metabolism 2020-07, Vol.319 (1), p.E217-E231
Hauptverfasser:	Yuan, Hao-Xiang, Chen, Cai-Yun, Li, Yu-Quan, Ning, Da-Sheng, Li, Yan, Chen, Ya-Ting, Li, Shang-Xuan, Fu, Meng-Xia, Li, Xiao-Di, Ma, Jian, Jian, Yu-Peng, Liu, Dong-Hong, Mo, Zhi-Wei, Peng, Yue-Ming, Xu, Kang-Qing, Ou, Zhi-Jun, Ou, Jing-Song
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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