Characterization of a Novel FLT3 BiTE Molecule for the Treatment of Acute Myeloid Leukemia

Despite advances in the treatment of acute myeloid leukemia (AML), novel therapies are needed to induce deeper and more durable clinical response. Bispecific T-cell Engager (BiTE) molecules, which redirect patient T cells to lyse tumor cells, are a clinically validated modality for hematologic malig...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Molecular cancer therapeutics 2020-09, Vol.19 (9), p.1875-1888
Hauptverfasser:	Brauchle, Bettina, Goldstein, Rebecca L., Karbowski, Christine M., Henn, Anja, Li, Chi-Ming, Bücklein, Veit L., Krupka, Christina, Boyle, Michael C., Koppikar, Priya, Haubner, Sascha, Wahl, Joachim, Dahlhoff, Christoph, Raum, Tobias, Rardin, Matthew J., Sastri, Christine, Rock, Dan A., von Bergwelt-Baildon, Michael, Frank, Brendon, Metzeler, Klaus H., Case, Ryan, Friedrich, Matthias, Balazs, Mercedesz, Spiekermann, Karsten, Coxon, Angela, Subklewe, Marion, Arvedson, Tara
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!