Decidual glycodelin-A polarizes human monocytes into a decidual macrophage-like phenotype through Siglec-7

Decidual macrophages constitute 20-30% of the total leukocytes in the uterus of pregnant women, regulating the maternal immune tolerance and placenta development. Abnormal number or activities of decidual macrophages (dMs) are associated with fetal loss and pregnancy complications, such as preeclamp...

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Veröffentlicht in:Journal of cell science 2020-07, Vol.133 (14)
Hauptverfasser: Vijayan, Madhavi, Lee, Cheuk-Lun, Wong, Vera H H, Wang, Xia, Bai, Kungfeng, Wu, Jian, Koistinen, Hannu, Seppälä, Markku, Lee, Kai-Fai, Yeung, William S B, Ng, Ernest H Y, Chiu, Philip C N
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