Hybrid membrane camouflaged copper sulfide nanoparticles for photothermal-chemotherapy of hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths worldwide. Biomimetic nanoparticles (NPs) coated with cell membranes show enhanced biocompatibility and specificity for homotypic cells, and have gained considerable attention for targeted anti-tumor therapy. We const...

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Veröffentlicht in:	Acta biomaterialia 2020-07, Vol.111, p.363-372
Hauptverfasser:	Ji, Bai, Cai, Hongqiao, Yang, Yang, Peng, Fenghui, Song, Meiyu, Sun, Kaiju, Yan, Fei, Liu, Yahui
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Phosphatidylinositol 3-kinase AKT protein Angiogenesis Animals Antibodies Biocompatibility Biomimetics Cancer Carcinoma, Hepatocellular - drug therapy Cell membranes Cell proliferation Chemotherapy Copper Copper - pharmacology Copper sulfides CuS nanoparticles Hepatocellular carcinoma Hepatoma Humans Irradiation Liver cancer Liver Neoplasms - drug therapy Macrophages Membrane proteins Membranes Mice Nanoparticles Near infrared radiation Phosphatidylinositol 3-Kinases Phototherapy Photothermal conversion Photothermal Therapy Radiation Raf protein Signaling Pathway Sorafenib Sulfides Tumor cells Tumors Vascular endothelial growth factor receptors
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