Glucosamine-NISV delivers antibody across the blood-brain barrier: Optimization for treatment of encephalitic viruses

The field of brain drug delivery faces many challenges that hinder development and testing of novel therapies for clinically important central nervous system disorders. Chief among them is how to deliver large biologics across the highly restrictive blood-brain barrier. Non-ionic surfactant vesicles...

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Veröffentlicht in:	Journal of controlled release 2020-08, Vol.324, p.644-656
Hauptverfasser:	Woods, Stuart, O'Brien, Lyn M., Butcher, Wendy, Preston, Jane E., Georgian, Ana R., Williamson, E. Diane, Salguero, F. Javier, Modino, Francesca, Abbott, N. Joan, Roberts, Craig W., D'Elia, Riccardo V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood-brain barrier Glucosamine GLUT1 Non-ionic surfactant vesicle Venezuelan equine encephalitis virus
Online-Zugang:	Volltext
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