Curcumin alleviates neuroinflammation, enhances hippocampal neurogenesis, and improves spatial memory after traumatic brain injury

•Curcumin rescued spatial memory after TBI in rats.•Curcumin decreased TBI-induced chronic neuroinflammation.•Curcumin increased hippocampal neurogenesis after TBI.•Curcumin may regulate these changes via the BNDF/Trkb/PI3K/AKT pathway. Cognitive decline is one of the most obvious symptoms of trauma...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Brain research bulletin 2020-09, Vol.162, p.84-93
Hauptverfasser:	Sun, Guangchi, Miao, Zong, Ye, Yangfan, Zhao, Pengzhan, Fan, Liang, Bao, Zhongyuan, Tu, Yiming, Li, Chong, Chao, Honglu, Xu, Xiupeng, Ji, Jing
Format:	Artikel
Sprache:	eng
Schlagworte:	Curcumin Inflammation Neurogenesis Traumatic brain injury
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!