Endophenotypic Variations of Atopic Dermatitis by Age, Race, and Ethnicity

Atopic dermatitis (AD) is a heterogeneous disease with unique clinical manifestations across age groups and race/ethnicities. Characteristic molecular mechanisms, known as endotypes, including IgE level, status of epidermal barrier genes, and differential cytokine axes activation in the background o...

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Veröffentlicht in:	The journal of allergy and clinical immunology in practice (Cambridge, MA) MA), 2020-06, Vol.8 (6), p.1840-1852
Hauptverfasser:	Nomura, Takashi, Wu, Jianni, Kabashima, Kenji, Guttman-Yassky, Emma
Format:	Artikel
Sprache:	eng
Schlagworte:	Accreditation Adult Adults Age Age groups Atopic dermatitis Biomarkers Child Cytokines Cytokines - genetics Dermatitis Dermatitis, Atopic - diagnosis Dermatitis, Atopic - epidemiology Dermatitis, Atopic - genetics Dupilumab Eczema Endotypes Epidemiology Ethnic Groups Ethnicity Filaggrin Genetics Helper cells Humans Immunoglobulin E Immunotherapy Lipid metabolism Lymphocytes T Medical education Molecular modelling Monoclonal antibodies Patients Pediatrics Phenotypes Physicians Polarity Precision medicine Race
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