Hybrid Modeling and Intensified DoE: An Approach to Accelerate Upstream Process Characterization

Process characterization is necessary in the biopharmaceutical industry, leading to concepts such as design of experiments (DoE) in combination with process modeling. However, these methods still have shortcomings, including large numbers of required experiments. The concept of intensified design of...

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Veröffentlicht in:	Biotechnology journal 2020-09, Vol.15 (9), p.e2000121-n/a
Hauptverfasser:	Bayer, Benjamin, Striedner, Gerald, Duerkop, Mark
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological Products Biomass Escherichia coli - genetics Humans Industry machine learning process control quality by design
Online-Zugang:	Volltext
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