Calpain inhibition ameliorates depression-like behaviors by reducing inflammation and promoting synaptic protein expression in the hippocampus

Protease activity correlates with depressive or suicidal behaviors, with calpain activation being especially implicated in depression-like behaviors. However, the role of calpain in depression-like behaviors is currently unknown. In this study, the lipopolysaccharide (LPS) - and chronic unpredictabl...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Neuropharmacology 2020-09, Vol.174, p.108175-108175, Article 108175
Hauptverfasser:	Song, Zhujin, Shen, Fengming, Zhang, Zhengrong, Wu, Shengbing, Zhu, Guoqi
Format:	Artikel
Sprache:	eng
Schlagworte:	Astrocyte Calpain Depression Hippocampus Synaptic
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!