Utility of measuring CSF hypocretin-1 level in patients with suspected narcolepsy

The patho-aetiology of narcolepsy Type I (NT1) is the loss of hypocretin-1 secreting neurons in the hypothalamus. Diagnostic criteria for NT1 include excessive daytime sleepiness (EDS) for at least three months not explained by any other condition, cataplexy and cerebrospinal fluid (CSF) hypocretin-...

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Veröffentlicht in:	Sleep medicine 2020-07, Vol.71, p.48-51
Hauptverfasser:	Gabryelska, Agata, Szmyd, Bartosz, Maschauer, Emily L., Roguski, Amber, Canham, Robyn, Morrison, Ian, Białasiewicz, Piotr, Riha, Renata L.
Format:	Artikel
Sprache:	eng
Schlagworte:	EDS Excessive daytime sleepiness Hypocretin-1 Narcolepsy Orexin
Online-Zugang:	Volltext
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