Recommended Guidelines for Developing, Qualifying, and Implementing Complex In Vitro Models (CIVMs) for Drug Discovery

The pharmaceutical industry is continuing to face high research and development (R&D) costs and low overall success rates of clinical compounds during drug development. There is an increasing demand for development and validation of healthy or disease-relevant and physiological human cellular mo...

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Veröffentlicht in:	SLAS discovery 2020-12, Vol.25 (10), p.1174-1190
Hauptverfasser:	Ekert, Jason E., Deakyne, Julianna, Pribul-Allen, Philippa, Terry, Rebecca, Schofield, Christopher, Jeong, Claire G., Storey, Joanne, Mohamet, Lisa, Francis, Jo, Naidoo, Anita, Amador, Alejandro, Klein, Jean-Louis, Rowan, Wendy
Format:	Artikel
Sprache:	eng
Schlagworte:	3D bioprinting 3D cell culture complex in vitro model efficacy functional genomics microphysiological systems organoids safety screening spheroid
Online-Zugang:	Volltext
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