The old CEACAMs find their new role in tumor immunotherapy

Summary Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) contain 12 family members(CEACAM1、CEACAM3、CEACAM4、CEACAM5、CEACAM6、CEACAM7、CEACAM8、CEACAM16、CEACAM18、CEACAM19、CEACAM20 and CEACAM21)and are expressed diversely in different normal and tumor tissues. CEA (CEACAM5) has been used...

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Veröffentlicht in:	Investigational new drugs 2020-12, Vol.38 (6), p.1888-1898
Hauptverfasser:	Han, Zi-Wen, Lyv, Zhi-Wu, Cui, Bin, Wang, Ying-Ying, Cheng, Jun-Ting, Zhang, Ying, Cai, Wen-Qi, Zhou, Yang, Ma, Zhao-Wu, Wang, Xian-Wang, Peng, Xiao-Chun, Cui, Shu-Zhong, Xiang, Ying, Yang, Mo, Xin, Hong-Wu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies Antigens Antigens, CD - chemistry Antigens, CD - immunology Biomarkers Bispecific antibodies Cancer immunotherapy Carcinoembryonic antigen CD66 antigen CEACAM1 protein Cell adhesion Cell adhesion & migration Cell adhesion molecules Cell Adhesion Molecules - chemistry Cell Adhesion Molecules - immunology Chimeric antigen receptors GPI-Linked Proteins - chemistry GPI-Linked Proteins - immunology Humans Immunotherapy Lymphocytes Lymphocytes T Medicine Medicine & Public Health Neoplasms - therapy Oncology Pharmacology/Toxicology R&D Research & development Review Tissues Tumors
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