HIF1A expression correlates with increased tumor immune and stromal signatures and aggressive phenotypes in human cancers

Background Although many studies have revealed essential roles of HIF1A (hypoxia inducible factor 1 subunit alpha) in regulating various pathways associated with cancer development, a systematic investigation of associations of HIF1A expression with tumor immunity, the tumor microenvironment and oth...

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Veröffentlicht in:	Cellular oncology (Dordrecht) 2020-10, Vol.43 (5), p.877-888
Hauptverfasser:	Chen, Baotao, Li, Lin, Li, Mengyuan, Wang, Xiaosheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Biomedical and Life Sciences Biomedicine Cancer Cancer Research Cell proliferation Hypoxia Immune response Immunotherapy Mesenchyme Metastases Oncology Original Paper Pathology PD-1 protein PD-L1 protein Phenotypes Signal transduction Tumors
Online-Zugang:	Volltext
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