Onset of Schamberg Disease and Resolution of Alopecia Areata During Treatment of Atopic Dermatitis With Dupilumab
Szekely et al the case of a 30-year-old patient affected by severe atopic dermatitis (AD) and alopecia areata (AA) on the scalp who developed a form of pigmented purpuric dermatosis, with concomitant improvement of AA during treatment with dupilumab for AD. Physical examination revealed severe eryth...
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| Veröffentlicht in: | Journal of investigational allergology & clinical immunology 2021-01, Vol.31 (1), p.65-66 |
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| container_title | Journal of investigational allergology & clinical immunology |
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| creator | Szekely, S Vaccari, D Salmaso, R Belloni-Fortina, A Alaibac, M |
| description | Szekely et al the case of a 30-year-old patient affected by severe atopic dermatitis (AD) and alopecia areata (AA) on the scalp who developed a form of pigmented purpuric dermatosis, with concomitant improvement of AA during treatment with dupilumab for AD. Physical examination revealed severe erythema, thickness, and lichenification affecting his entire body. AD is a chronic pruritic immunemediated inflammatory dermatosis with a high prevalence both in children and in adults. Its pathogenesis is multifactorial, including genetic, immunological, and environmental factors that cause skin barrier dysfunction, alterations in cell-mediated immune responses, and IgE-mediated hypersensitivity. AA is an autoimmune nonscarring alopecia with heterogeneous severity that affects up to 2% of the general population. |
| doi_str_mv | 10.18176/jiaci.0541 |
| format | Article |
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Physical examination revealed severe erythema, thickness, and lichenification affecting his entire body. AD is a chronic pruritic immunemediated inflammatory dermatosis with a high prevalence both in children and in adults. Its pathogenesis is multifactorial, including genetic, immunological, and environmental factors that cause skin barrier dysfunction, alterations in cell-mediated immune responses, and IgE-mediated hypersensitivity. AA is an autoimmune nonscarring alopecia with heterogeneous severity that affects up to 2% of the general population.</description><identifier>ISSN: 1018-9068</identifier><identifier>EISSN: 1698-0808</identifier><identifier>DOI: 10.18176/jiaci.0541</identifier><identifier>PMID: 32490817</identifier><language>eng</language><publisher>Spain: Esmon Publicidad</publisher><subject>Alopecia ; Atopic dermatitis ; Baldness ; Dermatitis ; Environmental factors ; Erythema ; Hypersensitivity ; Immune response (cell-mediated) ; Immunoglobulin E ; Inflammation ; Monoclonal antibodies ; Scalp ; Skin diseases</subject><ispartof>Journal of investigational allergology & clinical immunology, 2021-01, Vol.31 (1), p.65-66</ispartof><rights>Copyright Esmon Publicidad 2021</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c354t-1b293fc11c718ced532bef38e0629a24096c729d000edebd2945970f06afcea03</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32490817$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Szekely, S</creatorcontrib><creatorcontrib>Vaccari, D</creatorcontrib><creatorcontrib>Salmaso, R</creatorcontrib><creatorcontrib>Belloni-Fortina, A</creatorcontrib><creatorcontrib>Alaibac, M</creatorcontrib><title>Onset of Schamberg Disease and Resolution of Alopecia Areata During Treatment of Atopic Dermatitis With Dupilumab</title><title>Journal of investigational allergology & clinical immunology</title><addtitle>J Investig Allergol Clin Immunol</addtitle><description>Szekely et al the case of a 30-year-old patient affected by severe atopic dermatitis (AD) and alopecia areata (AA) on the scalp who developed a form of pigmented purpuric dermatosis, with concomitant improvement of AA during treatment with dupilumab for AD. Physical examination revealed severe erythema, thickness, and lichenification affecting his entire body. AD is a chronic pruritic immunemediated inflammatory dermatosis with a high prevalence both in children and in adults. Its pathogenesis is multifactorial, including genetic, immunological, and environmental factors that cause skin barrier dysfunction, alterations in cell-mediated immune responses, and IgE-mediated hypersensitivity. AA is an autoimmune nonscarring alopecia with heterogeneous severity that affects up to 2% of the general population.</description><subject>Alopecia</subject><subject>Atopic dermatitis</subject><subject>Baldness</subject><subject>Dermatitis</subject><subject>Environmental factors</subject><subject>Erythema</subject><subject>Hypersensitivity</subject><subject>Immune response (cell-mediated)</subject><subject>Immunoglobulin E</subject><subject>Inflammation</subject><subject>Monoclonal antibodies</subject><subject>Scalp</subject><subject>Skin diseases</subject><issn>1018-9068</issn><issn>1698-0808</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNpdkctLxDAQh4Movk_eJeBFkOok6SM5Lq4vWFjwgceSplPN0jY1SQ_-93bXx8HTzMA3H8P8CDlhcMkkK_KrldXGXkKWsi2yz3IlE5Agt6cemEwU5HKPHISwAhBFLotdsid4qmDa3Scfyz5gpK6hT-ZddxX6Nzq3AXVAqvuaPmJw7Rit69fMrHUDGqvpzKOOms5Hb_s3-ryeOuw3nll0gzV0jr7T0UYb6KuN7xM62HbsdHVEdhrdBjz-qYfk5fbm-fo-WSzvHq5ni8SILI0Jq7gSjWHMFEwarDPBK2yERMi50jwFlZuCqxoAsMaq5irNVAEN5LoxqEEckvNv7-Ddx4ghlp0NBttW9-jGUK4VTImUZRN69g9dudH303UlzyDlecqVmqiLb8p4F4LHphy87bT_LBmUmyTKTRLlOomJPv1xjlWH9R_7-3rxBW-jhGY</recordid><startdate>20210101</startdate><enddate>20210101</enddate><creator>Szekely, S</creator><creator>Vaccari, D</creator><creator>Salmaso, R</creator><creator>Belloni-Fortina, A</creator><creator>Alaibac, M</creator><general>Esmon Publicidad</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>20210101</creationdate><title>Onset of Schamberg Disease and Resolution of Alopecia Areata During Treatment of Atopic Dermatitis With Dupilumab</title><author>Szekely, S ; Vaccari, D ; Salmaso, R ; Belloni-Fortina, A ; Alaibac, M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c354t-1b293fc11c718ced532bef38e0629a24096c729d000edebd2945970f06afcea03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Alopecia</topic><topic>Atopic dermatitis</topic><topic>Baldness</topic><topic>Dermatitis</topic><topic>Environmental factors</topic><topic>Erythema</topic><topic>Hypersensitivity</topic><topic>Immune response (cell-mediated)</topic><topic>Immunoglobulin E</topic><topic>Inflammation</topic><topic>Monoclonal antibodies</topic><topic>Scalp</topic><topic>Skin diseases</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Szekely, S</creatorcontrib><creatorcontrib>Vaccari, D</creatorcontrib><creatorcontrib>Salmaso, R</creatorcontrib><creatorcontrib>Belloni-Fortina, A</creatorcontrib><creatorcontrib>Alaibac, M</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of investigational allergology & clinical immunology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Szekely, S</au><au>Vaccari, D</au><au>Salmaso, R</au><au>Belloni-Fortina, A</au><au>Alaibac, M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Onset of Schamberg Disease and Resolution of Alopecia Areata During Treatment of Atopic Dermatitis With Dupilumab</atitle><jtitle>Journal of investigational allergology & clinical immunology</jtitle><addtitle>J Investig Allergol Clin Immunol</addtitle><date>2021-01-01</date><risdate>2021</risdate><volume>31</volume><issue>1</issue><spage>65</spage><epage>66</epage><pages>65-66</pages><issn>1018-9068</issn><eissn>1698-0808</eissn><abstract>Szekely et al the case of a 30-year-old patient affected by severe atopic dermatitis (AD) and alopecia areata (AA) on the scalp who developed a form of pigmented purpuric dermatosis, with concomitant improvement of AA during treatment with dupilumab for AD. Physical examination revealed severe erythema, thickness, and lichenification affecting his entire body. AD is a chronic pruritic immunemediated inflammatory dermatosis with a high prevalence both in children and in adults. Its pathogenesis is multifactorial, including genetic, immunological, and environmental factors that cause skin barrier dysfunction, alterations in cell-mediated immune responses, and IgE-mediated hypersensitivity. AA is an autoimmune nonscarring alopecia with heterogeneous severity that affects up to 2% of the general population.</abstract><cop>Spain</cop><pub>Esmon Publicidad</pub><pmid>32490817</pmid><doi>10.18176/jiaci.0541</doi><tpages>2</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Journal of investigational allergology & clinical immunology, 2021-01, Vol.31 (1), p.65-66 |
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| source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Alopecia Atopic dermatitis Baldness Dermatitis Environmental factors Erythema Hypersensitivity Immune response (cell-mediated) Immunoglobulin E Inflammation Monoclonal antibodies Scalp Skin diseases |
| title | Onset of Schamberg Disease and Resolution of Alopecia Areata During Treatment of Atopic Dermatitis With Dupilumab |
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