Chronic Migraine With Apparent Loss of Response to Onabotulinum Toxin Type A Due to Local Nitroglycerin Treatment for an Anal Fissure: A Case Report

Chronic Migraine With Apparent Loss of Response to Onabotulinum Toxin Type A Due to Local Nitroglycerin Treatment for an Anal Fissure: A Case Report

Many patients with chronic migraine are difficult to treat. We present a patient with chronic migraine with good response to onabotulinum toxin type A whose headaches worsened in clear temporal relationship to local treatment with glyceryl trinitrate for an anal fissure. Our case shows that the use,...

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Veröffentlicht in:Headache 2020-11, Vol.60 (10), p.2570-2572
Hauptverfasser: Pérez‐Pereda, Sara, González‐Quintanilla, Vicente, Madera, Jorge, Pascual, Julio
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Sprache:eng
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Case reports
chronic migraine
Headache
Migraine
Nitric oxide
Nitroglycerin
onabotulinum toxin type A
Toxins
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container_end_page 2572
container_issue 10
container_start_page 2570
container_title Headache
container_volume 60
creator Pérez‐Pereda, Sara
González‐Quintanilla, Vicente
Madera, Jorge
Pascual, Julio
description Many patients with chronic migraine are difficult to treat. We present a patient with chronic migraine with good response to onabotulinum toxin type A whose headaches worsened in clear temporal relationship to local treatment with glyceryl trinitrate for an anal fissure. Our case shows that the use, even at distance, of nitric oxide donors can be a precipitating factor for migraineurs and should be always inquired in chronic migraine patients. In addition, the presence of frequent headaches should always be ruled out before prescribing such medications.
doi_str_mv 10.1111/head.13863
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source Wiley Online Library Journals Frontfile Complete
subjects Case reports
chronic migraine
Headache
Migraine
Nitric oxide
Nitroglycerin
onabotulinum toxin type A
Toxins
title Chronic Migraine With Apparent Loss of Response to Onabotulinum Toxin Type A Due to Local Nitroglycerin Treatment for an Anal Fissure: A Case Report
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