Multitargeted Compounds Derived from (2,5-Dioxopyrrolidin-1-yl)(phenyl)-Acetamides as Candidates for Effective Anticonvulsant and Antinociceptive Agents

We developed a focused set of original hybrid pyrrolidine-2,5-dione derivatives with potent anticonvulsant and antinociceptive properties. These hybrid compounds demonstrated broad-spectrum protective activity in a range of mouse models, such as the maximal electroshock (MES) test, the pentylenetetr...

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Veröffentlicht in:	ACS chemical neuroscience 2020-07, Vol.11 (13), p.1996-2008
Hauptverfasser:	Abram, Michał, Rapacz, Anna, Mogilski, Szczepan, Latacz, Gniewomir, Lubelska, Annamaria, Kamiński, Rafał M, Kamiński, Krzysztof
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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