Inducible nitric oxide synthase plays a role in depression- and anxiety-like behaviors chronically induced by lipopolysaccharide in rats: Evidence from inflammation and oxidative stress

•LPS injection was followed by neuroinflammation status in the brain.•The neuroinflammation was accompanied with oxidative stress status.•The neuroinflammation and oxidative stress was followed by depression and anxiety.•Aminoguanidine improved depression and anxiety and decreased oxidative stress.•...

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Veröffentlicht in:	Behavioural brain research 2020-08, Vol.392, p.112720-112720, Article 112720
Hauptverfasser:	Beheshti, Farimah, Hashemzehi, Milad, Hosseini, Mahmoud, Marefati, Narges, Memarpour, Sara
Format:	Artikel
Sprache:	eng
Schlagworte:	Aminoguanidine Anxiety Depression Lipopolysaccharide Neuroinflammation Oxidative stress
Online-Zugang:	Volltext
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