Xiaoyaosan decoction alleviated rat liver fibrosis via the TGFβ/Smad and Akt/FoxO3 signaling pathways based on network pharmacology analysis

Liver fibrosis is an outcome of many chronic liver diseases and often results in cirrhosis, liver failure, and even hepatocarcinoma. Xiaoyaosan decoction (XYS) as a classical Traditional Chinese Medicine (TCM) formula is used to liver fibrosis in clinical practice while its mechanism is unclear. The...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of ethnopharmacology 2021-01, Vol.264, p.113021-113021, Article 113021
Hauptverfasser:	Zhou, Yuan, Wu, Rong, Cai, Fei-Fei, Zhou, Wen-Jun, Lu, Yi-Yu, Zhang, Hui, Chen, Qi-Long, Su, Shi-Bing
Format:	Artikel
Sprache:	eng
Schlagworte:	Akt/FoxO3 signaling pathway Animals Drugs, Chinese Herbal - pharmacology Drugs, Chinese Herbal - therapeutic use Forkhead Box Protein O3 - antagonists & inhibitors Forkhead Box Protein O3 - metabolism Liver Cirrhosis - drug therapy Liver Cirrhosis - metabolism Liver fibrosis Male Network pharmacology Protein Interaction Maps - drug effects Protein Interaction Maps - physiology Proto-Oncogene Proteins c-akt - antagonists & inhibitors Proto-Oncogene Proteins c-akt - metabolism Rats Rats, Wistar Signal Transduction - drug effects Signal Transduction - physiology Smad3 Protein - antagonists & inhibitors Smad3 Protein - metabolism TGFβ/smad signaling pathway Transforming Growth Factor beta - antagonists & inhibitors Transforming Growth Factor beta - metabolism Xiaoyaosan decoction
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!