Validation of Whole Blood Rapid Diagnosis Test for Hepatitis B

Validation of Whole Blood Rapid Diagnosis Test for Hepatitis B

We recently published a report validating point-of-care rapid diagnostic tests (RDT) for the diagnosis of Hepatitis B virus (HBV) infection in serum. In the current report, we validated a whole-blood RDT for HBsAg in the form of a test-strip. The test was validated in 55 HBV positive individuals acr...

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Veröffentlicht in:Annals of global health 2020-05, Vol.86 (1), p.53-53, Article 53
Hauptverfasser: Debes, Jose D., van Oord, Gertine, Boonstra, Andre
Format: Artikel
Sprache:eng
Schlagworte:
Antigens
Blood
Data analysis
Diagnosis
Diagnostic tests
Genotypes
Hepatitis
Hepatitis B
Hepatitis B surface antigen
Infections
Letters to the Editor
Life Sciences & Biomedicine
Public, Environmental & Occupational Health
Science & Technology
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Beschreibung
Zusammenfassung:We recently published a report validating point-of-care rapid diagnostic tests (RDT) for the diagnosis of Hepatitis B virus (HBV) infection in serum. In the current report, we validated a whole-blood RDT for HBsAg in the form of a test-strip. The test was validated in 55 HBV positive individuals across all genotypes other than F, and in 20 HBV negative individuals in the Netherlands. The RDT showed 100% sensitivity and specificity. The low cost and use in whole blood allows this RDT to be useful in resource-limited locations, further validation in such settings will be of importance.
ISSN:2214-9996
2214-9996
DOI:10.5334/aogh.2866