Functional characterization of T3SS C-ring component VscQ and evaluation of its mutant as a live attenuated vaccine in zebrafish (Danio rerio) model

Vibrio alginolyticus, a Gram-negative bacterium, has been recognized as an opportunistic pathogen in marine animals as well as humans. Type III secretion system (T3SS) is critical for pathogen virulence and disease development. However, no more information is known about the C-ring component VscQ an...

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Veröffentlicht in:	Fish & shellfish immunology 2020-09, Vol.104, p.123-132
Hauptverfasser:	Wu, Peiwen, Zhou, Shihui, Su, Zehui, Liu, Chang, Zeng, Fuyuan, Pang, Huanying, Xie, Miao, Jian, Jichang
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bacterial Vaccines - immunology Fish Diseases - immunology Genes, Bacterial Live attenuated vaccines T3SS Type III Secretion Systems - immunology Vaccines, Attenuated - immunology Vibrio alginolyticus Vibrio alginolyticus - physiology Vibrio Infections - immunology Vibrio Infections - veterinary vscQ Zebrafish - immunology
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