Multifarious roles of mTOR signaling in cognitive aging and cerebrovascular dysfunction of Alzheimer's disease

Age‐related cognitive failure is a main devastating incident affecting even healthy people. Alzheimer's disease (AD) is the utmost common form of dementia among the geriatric community. In the pathogenesis of AD, cerebrovascular dysfunction is revealed before the beginning of the cognitive decl...

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Veröffentlicht in:	IUBMB life 2020-09, Vol.72 (9), p.1843-1855
Hauptverfasser:	Uddin, Md. Sahab, Rahman, Md. Ataur, Kabir, Md. Tanvir, Behl, Tapan, Mathew, Bijo, Perveen, Asma, Barreto, George E., Bin‐Jumah, May N., Abdel‐Daim, Mohamed M., Ashraf, Ghulam Md
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Alzheimer's disease Blood flow Blood-brain barrier Cerebral blood flow cerebrovascular dysfunction Cognitive ability cognitive aging Dementia disorders Hyperactivity Molecular modelling mTOR Neurodegenerative diseases Pathogenesis Rapamycin TOR protein
Online-Zugang:	Volltext
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