Connectomic signatures of working memory deficits in depression, mania, and euthymic states of bipolar disorder

•A putative state-dependent mechanistic link between connectome topology, hub re-distribution and impaired n-back performance in different phases of BD was demonstrated.•The aberrant task-dependent modulation of the connectome relates to worse WM performance especially when anxiety and depression ar...

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Veröffentlicht in:	Journal of affective disorders 2020-09, Vol.274, p.190-198
Hauptverfasser:	Yang, Jie, Ouyang, Xuan, Tao, Haojuan, Pu, Weidan, Fan, Zebin, Zeng, Can, Huang, Xiaojun, Chen, Xudong, Liu, Jun, Liu, Zhening, Palaniyappan, Lena
Format:	Artikel
Sprache:	eng
Schlagworte:	Bipolar disorder Bipolar Disorder - complications Connectome Depression Functional connectome Graph theory Humans Magnetic Resonance Imaging Mania Memory Disorders Memory, Short-Term Neural efficiency Working memory
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