Accelerated healing by topical administration of Salvia officinalis essential oil on Pseudomonas aeruginosa and Staphylococcus aureus infected wound model

Accelerative effect of SOO on infected wound healing; (A) by inhibition in bacteria colonization and growth, (B) by up-regulating the expression of IL-1β, IL-6 and TNF-α as pro-inflammatory cytokines and modulating tissue inflammation. (C) by raising the TAC level and reduced MDA content. (D) by up-...

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Veröffentlicht in:	Biomedicine & pharmacotherapy 2020-08, Vol.128, p.110120-110120, Article 110120
Hauptverfasser:	Farahpour, Mohammad Reza, Pirkhezr, Ehsan, Ashrafian, Ali, Sonboli, Ali
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Cutaneous Angiogenesis Animals Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - isolation & purification Collagen deposition Cyclin D1 - genetics Cyclin D1 - metabolism Cytokines - genetics Cytokines - metabolism Disease Models, Animal Fibroblast Growth Factor 2 - genetics Fibroblast Growth Factor 2 - metabolism Infected wound healing Inflammation Inflammation Mediators - metabolism Male Mice, Inbred BALB C Oils, Volatile - administration & dosage Oils, Volatile - isolation & purification Plant Oils - administration & dosage Plant Oils - isolation & purification Proto-Oncogene Proteins c-bcl-2 - genetics Proto-Oncogene Proteins c-bcl-2 - metabolism Pseudomonas Infections - drug therapy Pseudomonas Infections - metabolism Pseudomonas Infections - microbiology Pseudomonas Infections - pathology Re-epithelialization Salvia officinalis - chemistry Salvia officinalis essential oil Staphylococcal Infections - drug therapy Staphylococcal Infections - metabolism Staphylococcal Infections - microbiology Staphylococcal Infections - pathology Time Factors Vascular Endothelial Growth Factor A - genetics Vascular Endothelial Growth Factor A - metabolism Wound Healing - drug effects Wound Infection - drug therapy Wound Infection - metabolism Wound Infection - microbiology Wound Infection - pathology
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