Effect of childhood physical abuse on social anxiety is mediated via reduced frontal lobe and amygdala-hippocampus complex volume in adult clinical high-risk subjects

Childhood adverse experiences (CAE) are associated with clinical psychiatric disorders and symptoms, and with volumetric abnormalities in the amygdala-hippocampus complex (AmHiC) and frontal lobe (FroL) in adulthood. To study whether CAE are associated with reduced AmHiC and FroL and whether these s...

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Veröffentlicht in:Schizophrenia research 2021-01, Vol.227, p.101-109
Hauptverfasser: Salokangas, R.K.R., Hietala, J., Armio, R.L., Laurikainen, H., From, T., Borgwardt, S., Riecher-Rössler, A., Brambilla, P., Bonivento, C., Meisenzahl, E., Schultze-Lutter, F., Haidl, T., Ruhrmann, S., Upthegrove, R., Wood, S.J., Pantelis, C., Kambeitz-Ilankovic, L., Ruef, A., Dwyer, D.B., Kambeitz, J., Koutsouleris, N.
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Sprache:eng
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