Single-nucleotide polymorphisms influence the promoter activities of systemic lupus erythematosus-associated genes

Systemic lupus erythematosus (SLE) is a protypical autoimmune disease and genetic factors play important roles in its pathogenesis. Since present SLE susceptibility loci are mainly studied through meta-analysis of genome-wide association study, we performed promoter activity analysis to examine the...

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Veröffentlicht in:	Biotechnology letters 2020-10, Vol.42 (10), p.1887-1896
Hauptverfasser:	Qiu, Jinjun, Qin, Xiaoming, Wen, Jinli, Wu, Li, Kong, Lei, Ou, Yangxi, Yang, Shucai
Format:	Artikel
Sprache:	eng
Schlagworte:	Applied Microbiology Autoimmune diseases Biochemistry Biomedical and Life Sciences Biotechnology Chronic conditions Genetic factors Genome-wide association studies Genomes Glucocorticoids Life Sciences Lupus Microbiology Nucleotides Original Research Paper Pathogenesis Single-nucleotide polymorphism Systemic lupus erythematosus
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