P‐glycoprotein and multidrug resistance‐associated protein‐1 expression in acute myeloid leukemia: Biological and prognosis implications

Background Despite the advances in the cure rate for acute myeloid leukemia (AML), a considerable number of patients die from the disease due to the occurrence of multidrug resistance (MDR). Overexpression of the transporter proteins, such as P‐glycoprotein (Pgp) and multidrug resistance‐associated...

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Veröffentlicht in:	International journal of laboratory hematology 2020-10, Vol.42 (5), p.594-603
Hauptverfasser:	da Silveira Júnior, Lenilton Silva, Soares, Victor de Lima, Jardim da Silva, Alessandra Suelen, Gil, Erica Aires, Pereira de Araújo, Maria das Graças, Merces Gonçalves, Ciro Alexandre, Paiva, Aldair de Souza, Moura de Oliveira, Taissa Maria, Oliveira, Gustavo Henrique de Medeiros, Kramer Cavacanti e Silva, Dany Geraldo, de Araújo Moura Lemos, Telma Maria, Moretti Rebecchi, Ivanise Marina, de Farias Sales, Valeria Soraya, Luchessi, André Ducati, Cavalcanti Júnior, Geraldo Barroso
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute myeloid leukemia Adolescent Adult Aged Aged, 80 and over ATP Binding Cassette Transporter, Subfamily B, Member 1 - genetics ATP Binding Cassette Transporter, Subfamily B, Member 1 - metabolism Biomarkers Biomarkers, Tumor Bone marrow CD34 antigen CD7 antigen Child Child, Preschool Drug Resistance, Multiple Drug Resistance, Neoplasm Female Flow Cytometry Glycoproteins Humans Immunophenotyping Infant Leukemia Leukemia, Myeloid, Acute - diagnosis Leukemia, Myeloid, Acute - genetics Leukemia, Myeloid, Acute - metabolism Leukemia, Myeloid, Acute - mortality Male Middle Aged Multidrug resistance Multidrug Resistance-Associated Proteins - genetics Multidrug Resistance-Associated Proteins - metabolism multidrug resistance‐associated protein1 Myeloid leukemia Patients Peripheral blood Phenotype Phenotypes Prognosis Protein transport P‐glycoprotein Symptom Assessment Young Adult
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