Farnesol attenuates oxidative stress and liver injury and modulates fatty acid synthase and acetyl-CoA carboxylase in high cholesterol-fed rats

Dyslipidemia is a risk factor for cardiovascular disease, steatohepatitis, and progression of liver disorders. This study investigated the protective effect of farnesol (FAR), a sesquiterpene alcohol, against liver injury in high cholesterol diet (HCD)-fed rats, and its modulatory effect on fatty ac...

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Veröffentlicht in:	Environmental science and pollution research international 2020-08, Vol.27 (24), p.30118-30132
Hauptverfasser:	Abukhalil, Mohammad H., Hussein, Omnia E., Bin-Jumah, May, Saghir, Sultan A. M., Germoush, Mousa O., Elgebaly, Hassan A., Mosa, Nermeen M., Hamad, Ismail, Qarmush, Moath M., Hassanein, Emad M., Kamel, Emadeldin M., Hernandez-Bautista, Rene, Mahmoud, Ayman M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetyl-CoA carboxylase Antioxidants Aquatic Pollution Atmospheric Protection/Air Quality Control/Air Pollution Cardiovascular diseases Cholesterol Cytokines Deregulation Dyslipidemia Earth and Environmental Science Ecotoxicology Environment Environmental Chemistry Environmental Health Environmental science Farnesol Fatty acids Fatty-acid synthase Health risks High cholesterol diet Hyperlipidemia Inflammation Injury prevention Lipid peroxidation Lipids Lipoproteins (very low density) Liver Liver diseases Low density lipoprotein Metabolic disorders Molecular docking mRNA Oxidants Oxidative stress Oxidizing agents Peroxidation Research Article Risk analysis Risk factors Rodents Transaminases Triglycerides Waste Water Technology Water Management Water Pollution Control
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