Global priority multidrug-resistant pathogens do not resist photodynamic therapy

Microbial drug-resistance demands immediate implementation of novel therapeutic strategies. Antimicrobial photodynamic therapy (aPDT) combines the administration of a photosensitizer (PS) compound with low-irradiance light to induce photochemical reactions that yield reactive oxygen species (ROS). S...

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Veröffentlicht in:	Journal of photochemistry and photobiology. B, Biology Biology, 2020-07, Vol.208, p.111893-111893, Article 111893
Hauptverfasser:	Sabino, Caetano Padial, Wainwright, Mark, Ribeiro, Martha Simões, Sellera, Fábio Parra, dos Anjos, Carolina, Baptista, Mauricio da Silva, Lincopan, Nilton
Format:	Artikel
Sprache:	eng
Schlagworte:	Aerogenes Antiinfectives and antibacterials Antimicrobial agents Bacteria Biomolecules Candida albicans - drug effects Cryptococcus neoformans Deactivation Drug resistance Drug Resistance, Microbial - drug effects E coli ESKAPE Fungi Gram-Negative Bacteria - drug effects Gram-Positive Bacteria - drug effects Inactivation Irradiance Kinetics Klebsiella Klebsiella pneumoniae Light Methylene blue Methylene Blue - pharmacology Microbial Sensitivity Tests Microorganisms Multidrug resistance Pathogens Phenotypes Photochemical reactions Photochemicals Photodynamic therapy Photoinactivation Photosensitizing Agents - pharmacology Pseudomonas aeruginosa Reaction kinetics Reactive oxygen species
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