The effects of cashew nut intake on lipid profile and blood pressure: A systematic review and meta-analysis of randomized controlled trials
•Dyslipidemia and hypertension are important risk factors for cardiovascular disease (CVD).•Cashew nut intake has favorable effect on blood pressure.•Cashew nut intake has not a significant effect on lipid profile. Dyslipidemia and hypertension are important risk factors for cardiovascular disease (...
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| Veröffentlicht in: | Complementary therapies in medicine 2020-05, Vol.50, p.102387-102387, Article 102387 |
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| container_title | Complementary therapies in medicine |
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| creator | Jalali, Mohammad Karamizadeh, Malihe Ferns, Gordon A. Zare, Morteza Moosavian, Seyedeh Parisa Akbarzadeh, Marzieh |
| description | •Dyslipidemia and hypertension are important risk factors for cardiovascular disease (CVD).•Cashew nut intake has favorable effect on blood pressure.•Cashew nut intake has not a significant effect on lipid profile.
Dyslipidemia and hypertension are important risk factors for cardiovascular disease (CVD). Some studies have suggested that the consumption of nuts may reduce CVD risk.
The present systematic review and meta-analysis was conducted to investigate the efficacy of cashew nut consumption on lipid profile and blood pressure.
PubMed, Embase, Scopus, Web of Science and Cochrane Library were systematically searched to identify randomized control trials (RCTs) examining the effects of cashew nut intake on serum triglycerides (TG), high density lipoprotein-cholesterol (HDL-C), low density lipoprotein-cholesterol (LDL-C), serum total cholesterol (TC), systolic blood pressure (SBP) or diastolic blood pressure (DBP) until 15 November 2019. A random-effects model was used to pool weighted mean difference (WMD) and 95 % confidence intervals (CI). Potential publication bias was assessed using Egger’s test. Sensitivity analysis was performed to assess the impact of each individual study on the pooled results.
A meta-analysis on 392 participants showed that cashew nut consumption had no significant effects on lipid profile and DBP. However, there was a significant reduction in SBP (WMD = -3.39, 95 % CI = [-6.13, -0.65], P = 0.01, I2 = 0.0 %) in the group receiving cashew nut compared to the controls. There was no significant publication bias in the meta-analysis. A sensitivity analysis showed that omitting each study did not change the significance of results.
This meta-analysis demonstrated that cashew nut consumption might reduce SBP but has no effects on lipid profile and DBP. |
| doi_str_mv | 10.1016/j.ctim.2020.102387 |
| format | Article |
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Dyslipidemia and hypertension are important risk factors for cardiovascular disease (CVD). Some studies have suggested that the consumption of nuts may reduce CVD risk.
The present systematic review and meta-analysis was conducted to investigate the efficacy of cashew nut consumption on lipid profile and blood pressure.
PubMed, Embase, Scopus, Web of Science and Cochrane Library were systematically searched to identify randomized control trials (RCTs) examining the effects of cashew nut intake on serum triglycerides (TG), high density lipoprotein-cholesterol (HDL-C), low density lipoprotein-cholesterol (LDL-C), serum total cholesterol (TC), systolic blood pressure (SBP) or diastolic blood pressure (DBP) until 15 November 2019. A random-effects model was used to pool weighted mean difference (WMD) and 95 % confidence intervals (CI). Potential publication bias was assessed using Egger’s test. Sensitivity analysis was performed to assess the impact of each individual study on the pooled results.
A meta-analysis on 392 participants showed that cashew nut consumption had no significant effects on lipid profile and DBP. However, there was a significant reduction in SBP (WMD = -3.39, 95 % CI = [-6.13, -0.65], P = 0.01, I2 = 0.0 %) in the group receiving cashew nut compared to the controls. There was no significant publication bias in the meta-analysis. A sensitivity analysis showed that omitting each study did not change the significance of results.
This meta-analysis demonstrated that cashew nut consumption might reduce SBP but has no effects on lipid profile and DBP.</description><identifier>ISSN: 0965-2299</identifier><identifier>EISSN: 1873-6963</identifier><identifier>DOI: 10.1016/j.ctim.2020.102387</identifier><identifier>PMID: 32444052</identifier><language>eng</language><publisher>Scotland: Elsevier Ltd</publisher><subject>Anacardiaceae ; Bias ; Blood pressure ; Cardiovascular disease ; Cardiovascular diseases ; Cashew nut ; Cholesterol ; Clinical trials ; Confidence intervals ; Consumption ; Density ; Diet ; Dietary guidelines ; Dyslipidemia ; Health risks ; High density lipoprotein ; Hypertension ; Lipid profile ; Lipids ; Low density lipoprotein ; Meta-analysis ; Nuts ; Oils & fats ; Randomization ; Review ; Risk analysis ; Risk factors ; Sensitivity analysis ; Systematic review ; Triglycerides</subject><ispartof>Complementary therapies in medicine, 2020-05, Vol.50, p.102387-102387, Article 102387</ispartof><rights>2020 Elsevier Ltd</rights><rights>Copyright © 2020 Elsevier Ltd. All rights reserved.</rights><rights>2020. Elsevier Ltd</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c428t-8072ce5590d60668228e4e3752e5f06e9f73e03268ed9af4bea0028f9f1deb4a3</citedby><cites>FETCH-LOGICAL-c428t-8072ce5590d60668228e4e3752e5f06e9f73e03268ed9af4bea0028f9f1deb4a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/2418073388?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,778,782,3539,27907,27908,45978,64366,64368,64370,72220</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32444052$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jalali, Mohammad</creatorcontrib><creatorcontrib>Karamizadeh, Malihe</creatorcontrib><creatorcontrib>Ferns, Gordon A.</creatorcontrib><creatorcontrib>Zare, Morteza</creatorcontrib><creatorcontrib>Moosavian, Seyedeh Parisa</creatorcontrib><creatorcontrib>Akbarzadeh, Marzieh</creatorcontrib><title>The effects of cashew nut intake on lipid profile and blood pressure: A systematic review and meta-analysis of randomized controlled trials</title><title>Complementary therapies in medicine</title><addtitle>Complement Ther Med</addtitle><description>•Dyslipidemia and hypertension are important risk factors for cardiovascular disease (CVD).•Cashew nut intake has favorable effect on blood pressure.•Cashew nut intake has not a significant effect on lipid profile.
Dyslipidemia and hypertension are important risk factors for cardiovascular disease (CVD). Some studies have suggested that the consumption of nuts may reduce CVD risk.
The present systematic review and meta-analysis was conducted to investigate the efficacy of cashew nut consumption on lipid profile and blood pressure.
PubMed, Embase, Scopus, Web of Science and Cochrane Library were systematically searched to identify randomized control trials (RCTs) examining the effects of cashew nut intake on serum triglycerides (TG), high density lipoprotein-cholesterol (HDL-C), low density lipoprotein-cholesterol (LDL-C), serum total cholesterol (TC), systolic blood pressure (SBP) or diastolic blood pressure (DBP) until 15 November 2019. A random-effects model was used to pool weighted mean difference (WMD) and 95 % confidence intervals (CI). Potential publication bias was assessed using Egger’s test. Sensitivity analysis was performed to assess the impact of each individual study on the pooled results.
A meta-analysis on 392 participants showed that cashew nut consumption had no significant effects on lipid profile and DBP. However, there was a significant reduction in SBP (WMD = -3.39, 95 % CI = [-6.13, -0.65], P = 0.01, I2 = 0.0 %) in the group receiving cashew nut compared to the controls. There was no significant publication bias in the meta-analysis. A sensitivity analysis showed that omitting each study did not change the significance of results.
This meta-analysis demonstrated that cashew nut consumption might reduce SBP but has no effects on lipid profile and DBP.</description><subject>Anacardiaceae</subject><subject>Bias</subject><subject>Blood pressure</subject><subject>Cardiovascular disease</subject><subject>Cardiovascular diseases</subject><subject>Cashew nut</subject><subject>Cholesterol</subject><subject>Clinical trials</subject><subject>Confidence intervals</subject><subject>Consumption</subject><subject>Density</subject><subject>Diet</subject><subject>Dietary guidelines</subject><subject>Dyslipidemia</subject><subject>Health risks</subject><subject>High density lipoprotein</subject><subject>Hypertension</subject><subject>Lipid profile</subject><subject>Lipids</subject><subject>Low density lipoprotein</subject><subject>Meta-analysis</subject><subject>Nuts</subject><subject>Oils & fats</subject><subject>Randomization</subject><subject>Review</subject><subject>Risk analysis</subject><subject>Risk 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trials</atitle><jtitle>Complementary therapies in medicine</jtitle><addtitle>Complement Ther Med</addtitle><date>2020-05</date><risdate>2020</risdate><volume>50</volume><spage>102387</spage><epage>102387</epage><pages>102387-102387</pages><artnum>102387</artnum><issn>0965-2299</issn><eissn>1873-6963</eissn><abstract>•Dyslipidemia and hypertension are important risk factors for cardiovascular disease (CVD).•Cashew nut intake has favorable effect on blood pressure.•Cashew nut intake has not a significant effect on lipid profile.
Dyslipidemia and hypertension are important risk factors for cardiovascular disease (CVD). Some studies have suggested that the consumption of nuts may reduce CVD risk.
The present systematic review and meta-analysis was conducted to investigate the efficacy of cashew nut consumption on lipid profile and blood pressure.
PubMed, Embase, Scopus, Web of Science and Cochrane Library were systematically searched to identify randomized control trials (RCTs) examining the effects of cashew nut intake on serum triglycerides (TG), high density lipoprotein-cholesterol (HDL-C), low density lipoprotein-cholesterol (LDL-C), serum total cholesterol (TC), systolic blood pressure (SBP) or diastolic blood pressure (DBP) until 15 November 2019. A random-effects model was used to pool weighted mean difference (WMD) and 95 % confidence intervals (CI). Potential publication bias was assessed using Egger’s test. Sensitivity analysis was performed to assess the impact of each individual study on the pooled results.
A meta-analysis on 392 participants showed that cashew nut consumption had no significant effects on lipid profile and DBP. However, there was a significant reduction in SBP (WMD = -3.39, 95 % CI = [-6.13, -0.65], P = 0.01, I2 = 0.0 %) in the group receiving cashew nut compared to the controls. There was no significant publication bias in the meta-analysis. A sensitivity analysis showed that omitting each study did not change the significance of results.
This meta-analysis demonstrated that cashew nut consumption might reduce SBP but has no effects on lipid profile and DBP.</abstract><cop>Scotland</cop><pub>Elsevier Ltd</pub><pmid>32444052</pmid><doi>10.1016/j.ctim.2020.102387</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
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| source | Elsevier ScienceDirect Journals; ProQuest Central UK/Ireland |
| subjects | Anacardiaceae Bias Blood pressure Cardiovascular disease Cardiovascular diseases Cashew nut Cholesterol Clinical trials Confidence intervals Consumption Density Diet Dietary guidelines Dyslipidemia Health risks High density lipoprotein Hypertension Lipid profile Lipids Low density lipoprotein Meta-analysis Nuts Oils & fats Randomization Review Risk analysis Risk factors Sensitivity analysis Systematic review Triglycerides |
| title | The effects of cashew nut intake on lipid profile and blood pressure: A systematic review and meta-analysis of randomized controlled trials |
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