Thymosin Alpha 1 Reduces the Mortality of Severe Coronavirus Disease 2019 by Restoration of Lymphocytopenia and Reversion of Exhausted T Cells

Abstract Background Thymosin alpha 1 (Tα1) had been used in the treatment of viral infections as an immune response modifier for many years. However, clinical benefits and the mechanism of Tα1 treatment for COVID-19 patients are still unclear. Methods We retrospectively reviewed the clinical outcome...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Clinical infectious diseases 2020-11, Vol.71 (16), p.2150-2157
Hauptverfasser:	Liu, Yueping, Pan, Yue, Hu, Zhenhong, Wu, Ming, Wang, Chenhui, Feng, Zeqing, Mao, Congzheng, Tan, Yingjun, Liu, Ying, Chen, Li, Li, Min, Wang, Gang, Yuan, Zilin, Diao, Bo, Wu, Yuzhang, Chen, Yongwen
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged CD4-Positive T-Lymphocytes - metabolism CD8-Positive T-Lymphocytes - metabolism COVID-19 - mortality COVID-19 - virology Female Humans Lymphopenia - metabolism Male Middle Aged Retrospective Studies SARS-CoV-2 - pathogenicity Thymalfasin - genetics Thymalfasin - metabolism Thymus Gland - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!