Ketamine’s dose related multiple mechanisms of actions: Dissociative anesthetic to rapid antidepressant

•Insight of rapid-acting antidepressant effects are reviewed.•Mechanisms of actions of metabolites are discussed.•Mechanisms for anesthetic and analgesia are briefly revisited. Ketamine induces safe and effective anesthesia and displays unusual cataleptic properties that gave rise to the term dissoc...

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Veröffentlicht in:	Behavioural brain research 2020-07, Vol.390, p.112631-112631, Article 112631
Hauptverfasser:	Lavender, Eli, Hirasawa-Fujita, Mika, Domino, Edward F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Dissociative effects Enantiomers Ketamine Mechanisms of action Metabolites Rapid antidepressant
Online-Zugang:	Volltext
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