The effects of length of femoral stem on aseptic loosening following cemented distal femoral endoprosthetic replacement in tumour surgery
Purpose Aseptic loosening is a common prosthetic failure mode. The purpose of this study was to identify dose-response relationship between length of femoral stem and aseptic loosening. Methods We collected data of patients who underwent distal femoral prosthetic replacements at our institution from...
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| Veröffentlicht in: | International orthopaedics 2020-07, Vol.44 (7), p.1427-1433 |
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| container_title | International orthopaedics |
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| creator | Zhang, Hao-ran Zhang, Jing-yu Yang, Xiong-gang Qiao, Rui-qi Li, Ji-kai Ren, Zhi-peng Hu, Yong-cheng |
| description | Purpose
Aseptic loosening is a common prosthetic failure mode. The purpose of this study was to identify dose-response relationship between length of femoral stem and aseptic loosening.
Methods
We collected data of patients who underwent distal femoral prosthetic replacements at our institution from 2001 to 2017. Cox regression and two-piecewise regression model were used to analyze the associations between stem length and aseptic loosening.
Results
Significant association of length of femoral stem with aseptic loosening was observed in multivariate model and a non-linear relationship could be found from the smoothed curve. In two-piecewise model, an inflection point was calculated to be 143 mm. On the left of the inflection point, every 1 mm increase in the length of stem indicated that the risk of aseptic loosening could be reduced by 6%.
Conclusion
There was a significant non-linear relationship between the length of femoral stem and aseptic loosening, and the inflection point was 143 mm. |
| doi_str_mv | 10.1007/s00264-020-04629-3 |
| format | Article |
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Aseptic loosening is a common prosthetic failure mode. The purpose of this study was to identify dose-response relationship between length of femoral stem and aseptic loosening.
Methods
We collected data of patients who underwent distal femoral prosthetic replacements at our institution from 2001 to 2017. Cox regression and two-piecewise regression model were used to analyze the associations between stem length and aseptic loosening.
Results
Significant association of length of femoral stem with aseptic loosening was observed in multivariate model and a non-linear relationship could be found from the smoothed curve. In two-piecewise model, an inflection point was calculated to be 143 mm. On the left of the inflection point, every 1 mm increase in the length of stem indicated that the risk of aseptic loosening could be reduced by 6%.
Conclusion
There was a significant non-linear relationship between the length of femoral stem and aseptic loosening, and the inflection point was 143 mm.</description><identifier>ISSN: 0341-2695</identifier><identifier>EISSN: 1432-5195</identifier><identifier>DOI: 10.1007/s00264-020-04629-3</identifier><identifier>PMID: 32435955</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Arthroplasty, Replacement, Hip - adverse effects ; Femur - diagnostic imaging ; Femur - surgery ; Hip Prosthesis - adverse effects ; Humans ; Medicine ; Medicine & Public Health ; Neoplasms ; Original Paper ; Orthopedics ; Prosthesis Design ; Prosthesis Failure ; Reoperation</subject><ispartof>International orthopaedics, 2020-07, Vol.44 (7), p.1427-1433</ispartof><rights>SICOT aisbl 2020</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c347t-60eb7ef047a7a4defbcea91423aebbf6e29a99f034ac71dad702b0f9aebd976a3</citedby><cites>FETCH-LOGICAL-c347t-60eb7ef047a7a4defbcea91423aebbf6e29a99f034ac71dad702b0f9aebd976a3</cites><orcidid>0000-0002-9846-6735</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00264-020-04629-3$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00264-020-04629-3$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27903,27904,41467,42536,51297</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32435955$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zhang, Hao-ran</creatorcontrib><creatorcontrib>Zhang, Jing-yu</creatorcontrib><creatorcontrib>Yang, Xiong-gang</creatorcontrib><creatorcontrib>Qiao, Rui-qi</creatorcontrib><creatorcontrib>Li, Ji-kai</creatorcontrib><creatorcontrib>Ren, Zhi-peng</creatorcontrib><creatorcontrib>Hu, Yong-cheng</creatorcontrib><title>The effects of length of femoral stem on aseptic loosening following cemented distal femoral endoprosthetic replacement in tumour surgery</title><title>International orthopaedics</title><addtitle>International Orthopaedics (SICOT)</addtitle><addtitle>Int Orthop</addtitle><description>Purpose
Aseptic loosening is a common prosthetic failure mode. The purpose of this study was to identify dose-response relationship between length of femoral stem and aseptic loosening.
Methods
We collected data of patients who underwent distal femoral prosthetic replacements at our institution from 2001 to 2017. Cox regression and two-piecewise regression model were used to analyze the associations between stem length and aseptic loosening.
Results
Significant association of length of femoral stem with aseptic loosening was observed in multivariate model and a non-linear relationship could be found from the smoothed curve. In two-piecewise model, an inflection point was calculated to be 143 mm. On the left of the inflection point, every 1 mm increase in the length of stem indicated that the risk of aseptic loosening could be reduced by 6%.
Conclusion
There was a significant non-linear relationship between the length of femoral stem and aseptic loosening, and the inflection point was 143 mm.</description><subject>Arthroplasty, Replacement, Hip - adverse effects</subject><subject>Femur - diagnostic imaging</subject><subject>Femur - surgery</subject><subject>Hip Prosthesis - adverse effects</subject><subject>Humans</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Neoplasms</subject><subject>Original Paper</subject><subject>Orthopedics</subject><subject>Prosthesis Design</subject><subject>Prosthesis Failure</subject><subject>Reoperation</subject><issn>0341-2695</issn><issn>1432-5195</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kc1uFDEQhC1ERJYkL8AB-chloP03jo8oIoAUiUtytjwz7d2JPPZie4TyCLw1XibhyMktdX0lVxch7xh8ZAD6UwHgveyAQwey56YTr8iOScE7xYx6TXYgJOt4b9Q5eVvKIwDT_TV7Q84Fl0IZpXbk9_0BKXqPYy00eRow7uvhNHlcUnaBlooLTZG6gsc6jzSkVDDOcU99CiH9Ok0jLhgrTnSaS23MC4txSsecSj3gCc14DG7T0jnSui5pzbSseY_56ZKceRcKXj2_F-Th9sv9zbfu7sfX7zef77pRSF27HnDQ6EFqp52c0A8jOsMkFw6HwffIjTPGt-hu1GxykwY-gDdtOxndO3FBPmy-7WM_VyzVLnMZMQQXMa3FcglKCHWteJPyTTq2DCWjt8c8Ly4_WQb2VIHdKrCtAvu3Aisa9P7Zfx0WnP4hLzdvArEJSlvFFt0-tjPElvl_tn8AzsWWdw</recordid><startdate>20200701</startdate><enddate>20200701</enddate><creator>Zhang, Hao-ran</creator><creator>Zhang, Jing-yu</creator><creator>Yang, Xiong-gang</creator><creator>Qiao, Rui-qi</creator><creator>Li, Ji-kai</creator><creator>Ren, Zhi-peng</creator><creator>Hu, Yong-cheng</creator><general>Springer Berlin Heidelberg</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-9846-6735</orcidid></search><sort><creationdate>20200701</creationdate><title>The effects of length of femoral stem on aseptic loosening following cemented distal femoral endoprosthetic replacement in tumour surgery</title><author>Zhang, Hao-ran ; Zhang, Jing-yu ; Yang, Xiong-gang ; Qiao, Rui-qi ; Li, Ji-kai ; Ren, Zhi-peng ; Hu, Yong-cheng</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c347t-60eb7ef047a7a4defbcea91423aebbf6e29a99f034ac71dad702b0f9aebd976a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Arthroplasty, Replacement, Hip - adverse effects</topic><topic>Femur - diagnostic imaging</topic><topic>Femur - surgery</topic><topic>Hip Prosthesis - adverse effects</topic><topic>Humans</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Neoplasms</topic><topic>Original Paper</topic><topic>Orthopedics</topic><topic>Prosthesis Design</topic><topic>Prosthesis Failure</topic><topic>Reoperation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zhang, Hao-ran</creatorcontrib><creatorcontrib>Zhang, Jing-yu</creatorcontrib><creatorcontrib>Yang, Xiong-gang</creatorcontrib><creatorcontrib>Qiao, Rui-qi</creatorcontrib><creatorcontrib>Li, Ji-kai</creatorcontrib><creatorcontrib>Ren, Zhi-peng</creatorcontrib><creatorcontrib>Hu, Yong-cheng</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>International orthopaedics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zhang, Hao-ran</au><au>Zhang, Jing-yu</au><au>Yang, Xiong-gang</au><au>Qiao, Rui-qi</au><au>Li, Ji-kai</au><au>Ren, Zhi-peng</au><au>Hu, Yong-cheng</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The effects of length of femoral stem on aseptic loosening following cemented distal femoral endoprosthetic replacement in tumour surgery</atitle><jtitle>International orthopaedics</jtitle><stitle>International Orthopaedics (SICOT)</stitle><addtitle>Int Orthop</addtitle><date>2020-07-01</date><risdate>2020</risdate><volume>44</volume><issue>7</issue><spage>1427</spage><epage>1433</epage><pages>1427-1433</pages><issn>0341-2695</issn><eissn>1432-5195</eissn><abstract>Purpose
Aseptic loosening is a common prosthetic failure mode. The purpose of this study was to identify dose-response relationship between length of femoral stem and aseptic loosening.
Methods
We collected data of patients who underwent distal femoral prosthetic replacements at our institution from 2001 to 2017. Cox regression and two-piecewise regression model were used to analyze the associations between stem length and aseptic loosening.
Results
Significant association of length of femoral stem with aseptic loosening was observed in multivariate model and a non-linear relationship could be found from the smoothed curve. In two-piecewise model, an inflection point was calculated to be 143 mm. On the left of the inflection point, every 1 mm increase in the length of stem indicated that the risk of aseptic loosening could be reduced by 6%.
Conclusion
There was a significant non-linear relationship between the length of femoral stem and aseptic loosening, and the inflection point was 143 mm.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>32435955</pmid><doi>10.1007/s00264-020-04629-3</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0002-9846-6735</orcidid></addata></record> |
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| ispartof | International orthopaedics, 2020-07, Vol.44 (7), p.1427-1433 |
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| language | eng |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; SpringerLink Journals - AutoHoldings |
| subjects | Arthroplasty, Replacement, Hip - adverse effects Femur - diagnostic imaging Femur - surgery Hip Prosthesis - adverse effects Humans Medicine Medicine & Public Health Neoplasms Original Paper Orthopedics Prosthesis Design Prosthesis Failure Reoperation |
| title | The effects of length of femoral stem on aseptic loosening following cemented distal femoral endoprosthetic replacement in tumour surgery |
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