3'UTRs Regulate Mouse Ntrk2 mRNA Distribution in Cortical Neurons

There are two major isoforms of NTRK2 (neurotrophic receptor tyrosine kinase 2, or TrkB), full-length isoform with tyrosine kinase (TK) domain intact (+) and spliced isoform without tyrosine kinase domain (TK(-)). Within each isoform, there exist subtypes with minor modifications of the protein sequ...

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Veröffentlicht in:	Journal of molecular neuroscience 2020-11, Vol.70 (11), p.1858-1870
Hauptverfasser:	Chen, Shangqin, Zhu, Jinjin, Li, Peijun, Xia, Zhaonan, Tu, Mengjing, Lin, Zhenlang, Xu, Baoji, Fu, Xiaoqin
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated Regions Animals Cells, Cultured Cerebral Cortex - cytology Male Membrane Glycoproteins - genetics Membrane Glycoproteins - metabolism Mice Mice, Inbred C57BL Neurons - metabolism Protein-Tyrosine Kinases - genetics Protein-Tyrosine Kinases - metabolism RNA Transport RNA, Messenger - genetics RNA, Messenger - metabolism Synaptosomes - metabolism
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