Molecular Mechanisms of ER Stress and UPR in the Pathogenesis of Alzheimer’s Disease

Alzheimer’s disease (AD) is a progressive neurodegenerative disease involving aggregation of misfolded proteins inside the neuron causing prolonged cellular stress. The neuropathological hallmarks of AD include the formation of senile plaques and neurofibrillary tangles in specific brain regions tha...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular neurobiology 2020-07, Vol.57 (7), p.2902-2919
Hauptverfasser:	Uddin, Md. Sahab, Tewari, Devesh, Sharma, Gaurav, Kabir, Md. Tanvir, Barreto, George E., Bin-Jumah, May N., Perveen, Asma, Abdel-Daim, Mohamed M., Ashraf, Ghulam Md
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - metabolism Alzheimer's disease Animals Antioxidants Biomedical and Life Sciences Biomedicine Brain - metabolism Cell Biology Cell survival Cellular stress response Disease Endoplasmic reticulum Endoplasmic Reticulum - metabolism Endoplasmic Reticulum Stress - physiology Humans Mitochondria Mitochondria - metabolism Molecular modelling Neurobiology Neurodegeneration Neurodegenerative diseases Neurofibrillary tangles Neurology Neurons - metabolism Neurosciences Oxidative stress Protein folding Proteins Reactive oxygen species Recovery of function Senile plaques Transcription Unfolded Protein Response - physiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!