Mapping the Minnesota Living with Heart Failure Questionnaire (MLHFQ) onto the Assessment of Quality of Life 8D (AQoL-8D) utility scores

Purpose The Minnesota Living with Heart Failure Questionnaire (MLHFQ) is a widely used condition-specific measure of quality of life (QoL) in patients with heart failure. To use information from the MLHFQ in an economic evaluation, the MLHFQ must be mapped onto a preference-based measure of QoL. Thi...

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Veröffentlicht in:Quality of life research 2020-10, Vol.29 (10), p.2815-2822
Hauptverfasser: Catchpool, Max, Ramchand, Jay, Hare, David L., Martyn, Melissa, Goranitis, Ilias
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container_end_page 2822
container_issue 10
container_start_page 2815
container_title Quality of life research
container_volume 29
creator Catchpool, Max
Ramchand, Jay
Hare, David L.
Martyn, Melissa
Goranitis, Ilias
description Purpose The Minnesota Living with Heart Failure Questionnaire (MLHFQ) is a widely used condition-specific measure of quality of life (QoL) in patients with heart failure. To use information from the MLHFQ in an economic evaluation, the MLHFQ must be mapped onto a preference-based measure of QoL. This study aims to develop a mapping algorithm between the MLHFQ and the Assessment of Quality of Life (AQoL) 8D utility instrument in patients with dilated cardiomyopathy (DCM). Methods MLHFQ and AQoL-8D data were collected on 61 Australian adults with idiopathic DCM or other non-hypertrophic cardiomyopathies. Three statistical methods were used as follows: ordinary least squares (OLS) regression, the robust MM estimator, and the generalised linear models (GLM). Each included a range of explanatory variables. Model performance was assessed using key goodness-of-fit measures, the mean absolute error (MAE), and the root-mean-square error (RMSE). Results The MLHFQ summary score and AQoL-8D utility scores were strongly correlated ( r  =  − 0.83, p  
doi_str_mv 10.1007/s11136-020-02531-4
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To use information from the MLHFQ in an economic evaluation, the MLHFQ must be mapped onto a preference-based measure of QoL. This study aims to develop a mapping algorithm between the MLHFQ and the Assessment of Quality of Life (AQoL) 8D utility instrument in patients with dilated cardiomyopathy (DCM). Methods MLHFQ and AQoL-8D data were collected on 61 Australian adults with idiopathic DCM or other non-hypertrophic cardiomyopathies. Three statistical methods were used as follows: ordinary least squares (OLS) regression, the robust MM estimator, and the generalised linear models (GLM). Each included a range of explanatory variables. Model performance was assessed using key goodness-of-fit measures, the mean absolute error (MAE), and the root-mean-square error (RMSE). Results The MLHFQ summary score and AQoL-8D utility scores were strongly correlated ( r  =  − 0.83, p  &lt; 0.0001) and the two subscales of the MLHFQ were correlated with the eight dimensions of the AQoL-8D. Utility scores were predicted with acceptable precision based on responses to the MLHFQ physical, emotional, social, and other subscales. OLS and GLM performed similarly with MAE and RMSE ranging 0.086–0.106 and 0.114–0.130, respectively. Conclusion The mapping algorithm developed in this study allows the derivation of AQoL-8D utilities from MLHFQ scores for use in cost-effectiveness analyses and most importantly, enables the economic evaluation of alternative heart failure therapy options when only the MLHFQ has been collected.</description><identifier>ISSN: 0962-9343</identifier><identifier>EISSN: 1573-2649</identifier><identifier>DOI: 10.1007/s11136-020-02531-4</identifier><identifier>PMID: 32424804</identifier><language>eng</language><publisher>Cham: Springer International Publishing</publisher><subject>Algorithms ; Female ; Heart Failure - diagnosis ; Humans ; Male ; Medicine ; Medicine &amp; Public Health ; Middle Aged ; Minnesota ; Public Health ; Quality of Life - psychology ; Quality of Life Research ; Sociology ; Surveys and Questionnaires</subject><ispartof>Quality of life research, 2020-10, Vol.29 (10), p.2815-2822</ispartof><rights>Springer Nature Switzerland AG 2020</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c347t-46369b7751e93ab750f7f7c96bb378b7cccc353d19d735ddf612effbd5803c633</citedby><cites>FETCH-LOGICAL-c347t-46369b7751e93ab750f7f7c96bb378b7cccc353d19d735ddf612effbd5803c633</cites><orcidid>0000-0001-7946-8324</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11136-020-02531-4$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11136-020-02531-4$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27923,27924,41487,42556,51318</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32424804$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Catchpool, Max</creatorcontrib><creatorcontrib>Ramchand, Jay</creatorcontrib><creatorcontrib>Hare, David L.</creatorcontrib><creatorcontrib>Martyn, Melissa</creatorcontrib><creatorcontrib>Goranitis, Ilias</creatorcontrib><title>Mapping the Minnesota Living with Heart Failure Questionnaire (MLHFQ) onto the Assessment of Quality of Life 8D (AQoL-8D) utility scores</title><title>Quality of life research</title><addtitle>Qual Life Res</addtitle><addtitle>Qual Life Res</addtitle><description>Purpose The Minnesota Living with Heart Failure Questionnaire (MLHFQ) is a widely used condition-specific measure of quality of life (QoL) in patients with heart failure. To use information from the MLHFQ in an economic evaluation, the MLHFQ must be mapped onto a preference-based measure of QoL. This study aims to develop a mapping algorithm between the MLHFQ and the Assessment of Quality of Life (AQoL) 8D utility instrument in patients with dilated cardiomyopathy (DCM). Methods MLHFQ and AQoL-8D data were collected on 61 Australian adults with idiopathic DCM or other non-hypertrophic cardiomyopathies. Three statistical methods were used as follows: ordinary least squares (OLS) regression, the robust MM estimator, and the generalised linear models (GLM). Each included a range of explanatory variables. Model performance was assessed using key goodness-of-fit measures, the mean absolute error (MAE), and the root-mean-square error (RMSE). Results The MLHFQ summary score and AQoL-8D utility scores were strongly correlated ( r  =  − 0.83, p  &lt; 0.0001) and the two subscales of the MLHFQ were correlated with the eight dimensions of the AQoL-8D. Utility scores were predicted with acceptable precision based on responses to the MLHFQ physical, emotional, social, and other subscales. OLS and GLM performed similarly with MAE and RMSE ranging 0.086–0.106 and 0.114–0.130, respectively. 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To use information from the MLHFQ in an economic evaluation, the MLHFQ must be mapped onto a preference-based measure of QoL. This study aims to develop a mapping algorithm between the MLHFQ and the Assessment of Quality of Life (AQoL) 8D utility instrument in patients with dilated cardiomyopathy (DCM). Methods MLHFQ and AQoL-8D data were collected on 61 Australian adults with idiopathic DCM or other non-hypertrophic cardiomyopathies. Three statistical methods were used as follows: ordinary least squares (OLS) regression, the robust MM estimator, and the generalised linear models (GLM). Each included a range of explanatory variables. Model performance was assessed using key goodness-of-fit measures, the mean absolute error (MAE), and the root-mean-square error (RMSE). Results The MLHFQ summary score and AQoL-8D utility scores were strongly correlated ( r  =  − 0.83, p  &lt; 0.0001) and the two subscales of the MLHFQ were correlated with the eight dimensions of the AQoL-8D. Utility scores were predicted with acceptable precision based on responses to the MLHFQ physical, emotional, social, and other subscales. OLS and GLM performed similarly with MAE and RMSE ranging 0.086–0.106 and 0.114–0.130, respectively. Conclusion The mapping algorithm developed in this study allows the derivation of AQoL-8D utilities from MLHFQ scores for use in cost-effectiveness analyses and most importantly, enables the economic evaluation of alternative heart failure therapy options when only the MLHFQ has been collected.</abstract><cop>Cham</cop><pub>Springer International Publishing</pub><pmid>32424804</pmid><doi>10.1007/s11136-020-02531-4</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0001-7946-8324</orcidid></addata></record>
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source MEDLINE; JSTOR Archive Collection A-Z Listing; SpringerLink Journals - AutoHoldings
subjects Algorithms
Female
Heart Failure - diagnosis
Humans
Male
Medicine
Medicine & Public Health
Middle Aged
Minnesota
Public Health
Quality of Life - psychology
Quality of Life Research
Sociology
Surveys and Questionnaires
title Mapping the Minnesota Living with Heart Failure Questionnaire (MLHFQ) onto the Assessment of Quality of Life 8D (AQoL-8D) utility scores
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