Comparative toxicity analysis of corannulene and benzo[a]pyrene in mice

•COR and BaP are metabolized by hepatic Cyp1a isozymes•COR and BaP alter intestinal microbiota•COR is a weak inducer of aryl hydrocarbon receptor•COR has less toxicological effect than BaP in mice Increasing production of corannulene (COR), a non-planar polycyclic aromatic hydrocarbon (PAH) with pro...

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Veröffentlicht in:	Toxicology letters 2020-10, Vol.331, p.130-142
Hauptverfasser:	Li, Gentao, Xiong, Hui, Saeed, Khawar, Ma, Ruicong, Xing, Yufeng, Bi, Yajuan, Li, Caiyu, Huang, Jianhui, Zhang, Youcai
Format:	Artikel
Sprache:	eng
Schlagworte:	Aryl hydrocarbon receptor Benzo[a]pyrene Corannulene Polycyclic aromatic hydrocarbon
Online-Zugang:	Volltext
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