Functional characterization of an immunity-related GTPase gene in immune defense from obscure puffer (Takifugu obscurus)

Immunity-related GTPases (IRGs) are a family of large interferon-inducible GTPases that function in effective host defense against invading pathogens. IRGs have been extensively studied in mammals for their roles in the elimination of intracellular pathogens; however, their homologs in lower vertebr...

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Veröffentlicht in:	Fish & shellfish immunology 2020-08, Vol.103, p.248-255
Hauptverfasser:	Hu, Sufei, Shi, Yan, Ding, Tie, Duan, Wen, Qiu, Ziyue, Zhao, Zhe
Format:	Artikel
Sprache:	eng
Schlagworte:	Aeromonas hydrophila - physiology Amino Acid Sequence Animals Antimicrobial function Edwardsiella tarda - physiology Enterobacteriaceae Infections - immunology Enterobacteriaceae Infections - veterinary Fish Diseases - immunology Fish Proteins - chemistry Fish Proteins - genetics Fish Proteins - immunology Gene Expression Profiling - veterinary Gene Expression Regulation - immunology Gram-Negative Bacterial Infections - immunology Gram-Negative Bacterial Infections - veterinary GTP Phosphohydrolases - chemistry GTP Phosphohydrolases - genetics GTP Phosphohydrolases - immunology Immunity, Innate - genetics Immunity-related GTPase Phylogeny Sequence Alignment - veterinary Subcellular localization Takifugu - genetics Takifugu - immunology Takifugu obscurus
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