How microRNAs affect the PD-L1 and its synthetic pathway in cancer

•PD-L1 is expressed on both hematopoietic and nonhematopoietic cells.•PD-L1 protect self-tissues from immune system attack.•Dysfunction of PD-L1 has been highlighted in the pathogenesis of tumors.•Several miRNAs play an important role in regulating PD-L1 in various malignancies. Programmed cell deat...

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Veröffentlicht in:	International immunopharmacology 2020-07, Vol.84, p.106594-106594, Article 106594
Hauptverfasser:	Danbaran, Gholamreza Rezaei, Aslani, Saeed, Sharafkandi, Nadia, Hemmatzadeh, Maryam, Hosseinzadeh, Ramin, Azizi, Gholamreza, Jadidi-Niaragh, Farhad, Babaie, Farhad, Mohammadi, Hamed
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Autoimmunity B7-H1 Antigen - biosynthesis Cancer Cancer therapy Cell death Cell surface Glycoproteins Humans Immune suppression Immune system Immunological tolerance microRNA MicroRNAs miRNA mRNA mRNA turnover Neoplasms - genetics Neoplasms - immunology Non-coding RNA Nucleotides Pathogenesis PD-L1 PD-L1 protein Tumors
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