Ruthenium-Catalyzed Highly Enantioselective Synthesis of cis -3-Quinuclidinols via DKR Asymmetric Transfer Hydrogenation

A method for the enantioselective synthesis of -3-quinuclidinols by Ru-catalyzed asymmetric transfer hydrogenation via dynamic kinetic resolution is described. The reaction proceeded under mild conditions using ammonium formate as the hydrogen donor, affording the products in high yields (up to 99%)...

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Veröffentlicht in:	Organic letters 2020-06, Vol.22 (11), p.4322-4326
Hauptverfasser:	Luo, Zhonghua, Wang, Zhongqing, Sun, Guodong, Jian, Weilin, Jiang, Fengkai, Luan, Baolei, Li, Ridong, Zhang, Lei
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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