CIGB-300 anticancer peptide regulates the protein kinase CK2-dependent phosphoproteome

Casein-kinase CK2 is a Ser/Thr protein kinase that fosters cell survival and proliferation of malignant cells. The CK2 holoenzyme, formed by the association of two catalytic alpha/alpha’ (CK2α/CK2α’) and two regulatory beta subunits (CK2β), phosphorylates diverse intracellular proteins partaking in...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular and cellular biochemistry 2020-07, Vol.470 (1-2), p.63-75
Hauptverfasser:	Perera, Yasser, Ramos, Yassel, Padrón, Gabriel, Caballero, Evelin, Guirola, Osmany, Caligiuri, Lorena G., Lorenzo, Norailys, Gottardo, Florencia, Farina, Hernán G., Filhol, Odile, Cochet, Claude, Perea, Silvio E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - pharmacology Binding Biochemistry Biomedical and Life Sciences Cancer Carcinoma, Non-Small-Cell Lung - metabolism Cardiology Care and treatment Casein Casein kinase II Casein Kinase II - metabolism Catalytic Domain Cell Line, Tumor Cell proliferation Cell survival Cell-Free System Enzymatic activity Enzymes Gene Expression Regulation, Neoplastic Humans Kinases Life Sciences Lung Neoplasms - metabolism Lysates Medical Biochemistry Microscopy, Fluorescence Oncology Peptides Peptides, Cyclic - pharmacology Phosphorylation Protein Binding Protein kinase C Protein kinases Proteins Proteome Recombinant Proteins - metabolism Substrate inhibition Substrates Target recognition Tumor cells
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!