Impact of mineralocorticoid receptor blockade with direct renin inhibition in angiotensin II-dependent hypertensive mice

It has been suggested that aldosterone breakthrough during treatment with a type 1 angiotensin II receptor (AT1R) blocker (ARB) may be an important risk factor for the progression of renal and cardiovascular disease. We examined whether the direct renin inhibitor, aliskiren caused aldosterone breakt...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Hypertension research 2020-10, Vol.43 (10), p.1099-1104
Hauptverfasser:	Hashimoto, Atsushi, Takeda, Yoshimichi, Karashima, Shigehiro, Kometani, Mitsuhiro, Aono, Daisuke, Demura, Masashi, Higashitani, Takuya, Konishi, Seigo, Yoneda, Takashi, Takeda, Yoshiyu
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood pressure Hypertension Sodium
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!