O -Alkyl Hydroxamates Display Potent and Selective Antileishmanial Activity

( ) causes visceral, cutaneous, and mucosal leishmaniasis in humans and canine leishmaniasis in dogs. Herein, we describe that -alkyl hydroxamate derivatives displayed potent and selective activity against the amastigote stage of while no activity was observed against promastigotes. Compound showed...

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Veröffentlicht in:Journal of medicinal chemistry 2020-06, Vol.63 (11), p.5734-5751
Hauptverfasser: Corpas-López, Victoriano, Tabraue-Chávez, Mavys, Sixto-López, Yudibeth, Panadero-Fajardo, Sonia, Alves de Lima Franco, Fernando, Domínguez-Seglar, José F, Morillas-Márquez, Francisco, Franco-Montalbán, Francisco, Díaz-Gavilán, Mónica, Correa-Basurto, José, López-Viota, Julián, López-Viota, Margarita, Pérez Del Palacio, José, de la Cruz, Mercedes, de Pedro, Nuria, Martín-Sánchez, Joaquina, Gómez-Vidal, José A
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Sprache:eng
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