Ginsenoside Mc1 improves liver steatosis and insulin resistance by attenuating ER stress

Ginsenoside, a major pharmacologically active ingredient in ginseng, has been known to exhibit beneficial properties such as antioxidant and anti-inflammatory effects. Ginsenoside compound Mc1 is one of the newly identified de-glycosylated ginsenosides. Endoplasmic reticulum (ER) stress has implicat...

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Veröffentlicht in:	Journal of ethnopharmacology 2020-09, Vol.259, p.112927-112927, Article 112927
Hauptverfasser:	Roh, Eun, Hwang, Hwan-Jin, Kim, Joo Won, Hong, So-hyeon, Kim, Jung A, Lee, You-Bin, Choi, Kyung Mook, Baik, Sei Hyun, Yoo, Hye Jin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - pharmacology Apoptosis - drug effects Diet, High-Fat - adverse effects Endoplasmic Reticulum Stress - drug effects ER stress Fatty Liver - drug therapy Fatty Liver - metabolism Ginsenoside Mc1 Ginsenosides - pharmacology Glucose Intolerance - metabolism Hep G2 Cells Hepatic steatosis Hepatocytes - drug effects Humans Insulin - metabolism Insulin Resistance Lipogenesis - drug effects Liver - drug effects Mice Mice, Inbred C57BL Mice, Obese Obesity Phosphorylation Signal Transduction - drug effects
Online-Zugang:	Volltext
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