Synergistic antidepressant-like effect of capsaicin and citalopram reduces the side effects of citalopram on anxiety and working memory in rats

Rationale We have previously shown that in rats, capsaicin (Cap) has antidepressant-like properties when assessed using the forced swimming test (FST) and that a sub-threshold dose of amitriptyline potentiates the effects of Cap. However, synergistic antidepressant-like effects of the joint administ...

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Veröffentlicht in:Psychopharmacology 2020-07, Vol.237 (7), p.2173-2185
Hauptverfasser: Aguilar-Martinez, Irving S., Reyes-Mendez, Miriam E., Herrera-Zamora, J. Manuel, Osuna-Lopez, Fernando, Virgen-Ortiz, Adolfo, Mendoza-Munoz, Nestor, Gongora-Alfaro, Jose L., Moreno-Galindo, Eloy G., Alamilla, Javier
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Sprache:eng
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