Assessing the hemostasis with thromboelastometry in direct oral anticoagulants-treated patients with atrial fibrillation
•This study tested the ability of ROTEM® to identify changes in hemostasis in a real-world sample of DOACs-treated (dabigatran, rivaroxaban, and apixaban-treated) patients with atrial fibrillation.•Comparing DOACs-treated patients to healthy controls, significant differences were found in trough and...
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| Veröffentlicht in: | Thrombosis research 2020-07, Vol.191, p.38-41 |
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| container_title | Thrombosis research |
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| creator | Korpallová, Barbora Samoš, Matej Škorňová, Ingrid Bolek, Tomáš Žolková, Jana Vadelová, Ľubica Kubisz, Peter Galajda, Peter Staško, Ján Mokáň, Marián |
| description | •This study tested the ability of ROTEM® to identify changes in hemostasis in a real-world sample of DOACs-treated (dabigatran, rivaroxaban, and apixaban-treated) patients with atrial fibrillation.•Comparing DOACs-treated patients to healthy controls, significant differences were found in trough and peak CT-INTEM®, CT-EXTEM®, CT-FIBTEM®, and MCF-FIBTEM® for dabigatran, rivaroxaban, and apixaban.•Furthermore, for rivaroxaban, significant differences in CT-INTEM®, CT-EXTEM®, CT-FIBTEM® were present when trough and peak samples were compared. |
| doi_str_mv | 10.1016/j.thromres.2020.04.038 |
| format | Article |
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| fulltext | fulltext |
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| ispartof | Thrombosis research, 2020-07, Vol.191, p.38-41 |
| issn | 0049-3848 1879-2472 |
| language | eng |
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| source | Access via ScienceDirect (Elsevier) |
| subjects | Atrial fibrillation Dabigatran Direct oral anticoagulants Oral factor Xa inhibitors Thromboelastometry |
| title | Assessing the hemostasis with thromboelastometry in direct oral anticoagulants-treated patients with atrial fibrillation |
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