Revisiting the development of small molecular inhibitors that directly target the signal transducer and activator of transcription 3 (STAT3) domains

Signal transducer and activator of transcription 3 (STAT3) has been a protein target following its roles being found to play in the progression of cancer development, cancer stemness, chemoresistance and radioresistance. Two decades of research efforts in STAT3 has, however, not yielded a marketed a...

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