Mitochondrial Delivery of an Anticancer Drug Via Systemic Administration Using a Mitochondrial Delivery System That Inhibits the Growth of Drug-Resistant Cancer Engrafted on Mice

Mitochondrial delivery of an anticancer drug targeting cancer cells would eventually result in cell death. To achieve this, a drug delivery system targeting mitochondria is needed. We recently developed a MITO-Porter, a liposome that delivers its cargo to mitochondria. We reported that such a MITO-P...

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Veröffentlicht in:	Journal of pharmaceutical sciences 2020-08, Vol.109 (8), p.2493-2500
Hauptverfasser:	Yamada, Yuma, Munechika, Reina, Satrialdi, Kubota, Fumika, Sato, Yusuke, Sakurai, Yu, Harashima, Hideyoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Drug-resistant cancer In vivo delivery Liposomes MITO-Porter Mitochondria Mitochondrial delivery
Online-Zugang:	Volltext
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