Mucoadhesive cholesterol-chitosan self-assembled particles for topical ocular delivery of dexamethasone

The topical application of ophthalmic drugs is a convenient and safe mode of drug administration. However, the bioavailability of topical drugs in the eye is low due to eye barriers and the rapid removal of the drug from the conjunctival surface by the tear fluid. The aim of this study was to obtain...

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Veröffentlicht in:	International journal of biological macromolecules 2020-09, Vol.158, p.811-818
Hauptverfasser:	Dubashynskaya, Natallia V., Golovkin, Alexey S., Kudryavtsev, Igor V., Prikhodko, Stanislava S., Trulioff, Andrey S., Bokatyi, Anton N., Poshina, Daria N., Raik, Sergei V., Skorik, Yury A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-inflammatory activity Cholesterol-chitosan Dexamethasone Mucoadhesion Ocular drug delivery Self-assembled particles
Online-Zugang:	Volltext
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