Interleukin-31 promotes pathogenic mechanisms underlying skin and lung fibrosis in scleroderma

Abstract Objectives Cytokines released by infiltrating T cells may promote mechanisms leading to fibrosis in scleroderma. The aim of this study was to investigate the role of the Th2 cytokine IL-31, and its receptor IL-31RA, in scleroderma skin and lung fibrosis. Methods IL-31 was measured by ELISA...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Rheumatology (Oxford, England) England), 2020-09, Vol.59 (9), p.2625-2636
Hauptverfasser:	Yaseen, Bodoor, Lopez, Henry, Taki, Zeinab, Zafar, Sara, Rosario, Henrique, Abdi, Bahja Ahmed, Vigneswaran, Shivanee, Xing, Fiona, Arumalla, Nikita, Black, Simon, Ahmad, Sara, Kumar, Kimti, Gul, Rabia, Scolamiero, Laura, Morris, Sian, Bowman, Alex, Stainer, Anna, Rice, Alexandra, Stock, Carmel, Renzoni, Elisabetta, Denton, Christopher P, Venturini, Cristina, Brown, Max, O’Reilly, Steven, Stratton, Richard
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Epigenesis, Genetic - immunology Fibroblasts - metabolism Fibrosis - immunology Humans Interleukins - immunology Lung - immunology Lung - pathology Mice Mice, Inbred BALB C Receptors, Interleukin - immunology Scleroderma, Systemic - immunology Scleroderma, Systemic - pathology Skin - immunology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!