Synthetic Guaiacol Derivatives as Promising Myeloperoxidase Inhibitors Targeting Atherosclerotic Cardiovascular Disease

Myeloperoxidase (MPO) is known to cause oxidative stress and inflammation leading to cardiovascular disease (CVD) complications. MPO‐mediated oxidation of lipoproteins leads to dysfunctional entities altering the landscape of lipoprotein functionality. The specificity of guaiacol derivatives toward...

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Veröffentlicht in:ChemMedChem 2020-07, Vol.15 (13), p.1187-1199
Hauptverfasser: Premkumar, Jayaraj, Sampath, Parthasarathy, Sanjay, Rajagopalan, Chandrakala, Aluganti, Rajagopal, Desikan
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Sprache:eng
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